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Filtered Search Results
Chemscene CHEMSCENE
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5000577170 ISOQUINOLIN-1-AMINE 100G
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Aobchem AOBCHEM
5000864463 1-BROMO-2 4-DIMETHOXY-5-METHYL
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Chemscene CHEMSCENE
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5000579627 4-BROMOISOQUINOLINE 10G
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Chemscene CHEMSCENE
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5000579619 4-BROMOISOQUINOLINE 100G
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Apexbio Technology LLC Elesclomol (STA-4783) 488832-69-5 200mg
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Elesclomol (STA-4783 CAS 488832-69-5) is a small molecule identified through phenotype-based screens for apoptotic activity which induces apoptosis in cancer cells by elevating intracellular reactive oxygen species (ROS) Its primary cellular target is mitochondrial electron transport disruption of which results in rapid accumulation of oxidative stress exceeding adaptive thresholds and ultimately triggering apoptotic cell death Elesclomol demonstrates antitumor activity across diverse human tumor xenograft models and is currently studied as an investigational anticancer compound capable of extending progression-free survival
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Apexbio Technology LLC Ki16198 355025-13-7 200mg
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Ki16198 (CAS 355025-13-7) is the methyl ester derivative of Ki16425 and functions as an antagonist of lysophosphatidic acid (LPA) receptors preferentially inhibiting LPA1 and LPA3 receptor subtypes Ki16198 reduces receptor-mediated inositol phosphate production with Ki values of 0 34 M (LPA1) and 0 93 M (LPA3) showing minimal inhibition of LPA2 and no significant activity against LPA4 6 In vitro Ki16198 attenuates LPA-induced proliferation migration invasion and proMMP-9 expression in cancer cells In vivo studies report suppression of pancreatic tumor growth metastasis and ascites formation highlighting its utility in investigating LPA-related cancer progression pathways
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Medchemexpress LLC Quin-C7 | 871100-12-8 | MFCD34182190 | 99.8% | 431.48 g/mol | C25H25N3O4 | 100 MG
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Quin-C7 is an orally active FPR2/ALX antagonist used in anti-inflammatory research, including dextran sulfate sodium (DSS)-induced colitis models. It is provided as a high-purity solid with characterized solubility and storage recommendations for both in vitro and in vivo studies.
- Orally active FPR2/ALX antagonist for anti-inflammatory research.
- Demonstrated efficacy in DSS-induced colitis models.
- High purity (≈99.8%) for reliable experimental results.
- White to off-white solid form, suitable for standard handling and storage.
- Soluble in DMSO at high concentration and formulatable for in vivo dosing.
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![eMolecules 92921-24-9 | Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt | Chem-Impex | MFCD00054978 | 436.370 | C16H17N2NaO9S | 96.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 50mg | 272386939](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000129261.jpg-250.jpg)
eMolecules 92921-24-9 | Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt | Chem-Impex | MFCD00054978 | 436.370 | C16H17N2NaO9S | 96.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 50mg | 272386939
Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt | Chem-Impex | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 96.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 50mg | 272386939
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Ambeed AMBEED
5000871161 METHYL 7-BROMOQUINOLINE-4- 1GR
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Apexbio Technology LLC RO4929097(Synonyms: RO-4929097, RO 4929097, Gamma-Secretase Inhibitor RO4929097, RO4929097 γ-secretase inhibitor), 200mg, CAS: 847925-91-1.
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RO4929097 (CAS 847925-91-1) is a potent selective small-molecule inhibitor of -secretase an essential protease in the Notch signaling pathway It inhibits -secretase with high specificity (IC50 4 nM EC50 5 nM) showing minimal inhibitory activity against closely related proteases and over 100-fold selectivity versus a broad spectrum of other proteases By preventing Notch receptor cleavage and subsequent signaling activation RO4929097 suppresses proliferation and tumorigenesis across various tumor models including melanoma breast colorectal pancreatic and lung cancers Clinical studies have assessed RO4929097 alone or combined with other anticancer agents for advanced solid tumors
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![eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Ambeed | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 5g | 571783243](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000490666.jpg-250.jpg)
eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Ambeed | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 5g | 571783243
4-Chloro-3-nitroquinoline | Ambeed | 39061-97-7 | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 5g | 571783243
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Medchemexpress LLC LED209 | 245342-14-7 | 98.4% | 383.49 | 200 MG
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LED209 is a potent and orally active small molecule inhibitor of the bacterial receptor QseC and a potent prodrug with high selectivity for QseC. It inhibits the binding of signaling molecules to QseC and exhibits antibacterial activity.
- Potent and orally active small molecule inhibitor of bacterial receptor QseC.
- Potent prodrug with high selectivity for QseC.
- Inhibits the binding of signaling molecules to QseC.
- Has antibacterial activity.
- Decreases biofilm formation in EAEC O104:H4 and multidrug-resistant clinical isolates of rUTIs.
- Reduces L. pneumophila replication.
- Protects mice against S. Typhimurium and F. tularensis murine infections.
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eMolecules 1952360-91-6 | (Fmoc-amino)-PEG12-C2-Carboxylic Acid | Accela ChemBio | MFCD08064302 | 839.973 | C42H65NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 796984240
(Fmoc-amino)-PEG12-C2-Carboxylic Acid | Accela ChemBio | 1952360-91-6 | MFCD08064302 | 839.973 | C42H65NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 796984240
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eMolecules 819058-34-9 | 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | Synthonix - Stock | MFCD09033884 | 237.080 | C12H17BFNO2 | 97.000 | CC1(C)OB(OC1(C)C)c1ccc(N)c(F)c1 | 10g | 483373764
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | Synthonix - Stock | 819058-34-9 | MFCD09033884 | 237.080 | C12H17BFNO2 | 97.000 | CC1(C)OB(OC1(C)C)c1ccc(N)c(F)c1 | 10g | 483373764
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Selleck Chemical LLC Acridine Orange hydrochloride
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Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA and green fluorescence when it binds to dsDNA (Ex 488 nM Em green fluorescence at 530 nm orange fluorescence at 640 nm)
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